Micky van de Ven Double Ends Everton's Unbeaten Streak at Brand New Stadium
The Dutch defender became the initial backline player to net twice in a Premier League game for Tottenham since Jan Vertonghen in spring 2013.
At a glance
Micky Van de Ven heads into the net two times in opening period
Everton's defender has equalizer ruled after VAR review
Pape Matar Sarr scores final goal in 89th minute
The defeat is the Merseyside club's first at their new ground
Micky van de Ven scored on two occasions as Spurs prolonged their winning streak on the road in the Premier League and delivered the Toffees their initial loss at their new home.
The Toffees were unbeaten in their five previous fixtures at their new ground at Bramley-Moore Dock, having left Goodison Park behind after more than a century at the conclusion of the previous campaign.
But Spurs captain Van de Ven struck twice from corners in the opening 45 minutes to place their strong form at risk, and they were failed to turn it around before the midfielder - assisted by former Toffees attacker the Brazilian - headed home a final goal to seal the victory.
Jake O'Brien believed he had levelled the tally five minutes after the defender's first goal, directing a bullet header past the Spurs keeper from an set-piece.
The Portuguese striker, in the meantime, failed to convert a number of opportunities, while the Italian goalkeeper made a series of fine stops to guarantee Tottenham went five away games without defeat in the Premier League.
But the VAR stepped in, advising Craig Pawson to review the score on the pitchside monitor and the official decided that Jack Grealish and Iliman Ndiaye were in an illegal position and had impeded with the Tottenham goalkeeper.
The win elevates Thomas Frank's side up to third in the division, a handful of points off local foes and table-toppers Arsenal.
Everton stay in 14th position and are half a dozen points clear of the relegation zone.
Tottenham analysis: Van de Ven excels in duties at both ends of pitch
Following a drab weekday performance in the Champions League against the French side, where they managed a mere attempts on goal, the manager chose Randal Kolo Muani up front instead of ex-Everton forward Richarlison.
The summer signing was unable to make much of an impact before being replaced for Richarlison after an hour on the field, but it emerged he wasn't needed in the end.
Centre-back the Dutchman converted into an offensive threat to be reckoned with.
Spurs' opening strike came from a cleverly executed set-piece play, with Rodrigo Bentancur directing the ball back across the face of goal for an unmarked the defender to head home.
And the captain - stepping up as captain in the Argentine's unavailability - added his next goal in first-half stoppage time as he outjumped Jordan Pickford to nod in.
Van de Ven was equally outstanding in defensive duties, combining well with Kevin Danso as the pair handled excellently with the numerous deliveries sent their way by the opposition.
Everton analysis: Toffees missing striker's instinct
Everton's new home had been a happy hunting ground, but it seems the freshness may have faded somewhat and fans flocked to the exits after the midfielder's final goal for Spurs.
The break in Everton's unbeaten home run won't be a massive worry for the manager, but their attacking woes are.
The forward and the other striker - the Toffees' pair of recognised strikers - had scored only one league goal between them before Sunday's match.
And they were unable to contribute to that poor record on a damp and dreary evening on in Liverpool.
The striker's form was epitomized when he chose to overhead kick a clear chance from close range, even with having space and opportunity to readjust for a more conventional shot that would have tested Vicario.
The substitute, as well, failed to influence the game after coming on for Beto in the second half.
It was not for a shortage of opportunity. Most of Everton's offensive moves came through Grealish and the forward, who tirelessly delivered threatening balls into the Spurs penalty area.
Upcoming fixtures for both teams?
Everton: Moyes' men head to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Spurs: The London club go to Newcastle's ground on late October for their next round League Cup tie against Newcastle.